Juneau, Alaska's capital and third-largest city, is on the North American mainland but can't be reached by road. Bounded by steep mountains and water, the city’s geographic isolation and compact size make it much more akin to an island community such as Sitka than to other Alaskan urban centers, such as Fairbanks or Anchorage. Juneau is full of contrasts. Its dramatic hillside location and historic downtown buildings provide a frontier feeling, but the city's cosmopolitan nature comes through in fine museums, noteworthy restaurants, and a literate and outdoorsy populace. The finest of the museums, the Alaska State Museum, is scheduled to reopen in May 2016 on its old site as the expanded Alaska State Library, Archives, and Museum (SLAM) following several years of planning and exhibit research. Another new facility, the Walter Soboleff Center, offers visitors a chance to learn about the indigenous cultures of Southeast Alaska–-Tlingit, Haida, and Tsimshian. Other highlights include the Mt. Roberts Tramway, plenty of densely forested wilderness areas, quiet bays for sea kayaking, and even a famous drive-up glacier, Mendenhall Glacier. For goings-on, pick up the Juneau Empire (www.juneauempire.com), which keeps tabs on state politics, business, sports, and local news.

As part of the Tracy Arm-Fords Terror Wilderness, Tracy Arm is within the Tongass National Forest. Tracy Arm is one of Alaska’s classic fjords. At the end of the narrow and almost 50 km long fjord, passing breathtaking mountains, steep cliffs and spectacular waterfalls, one can see the twin Sawyer Glaciers, South Sawyer and North Sawyer, active tidewater glaciers. Wildlife of the area includes whales, harbor seals, eagles, kittiwakes, Arctic Terns and Pigeon Guillemots.

A small, unassuming timber and fishing community, Wrangel sits on the northern tip of Wrangel Island, near the mouth of the fast-flowing Stikine River—North America's largest undammed river. The Stikine plays a large role in the life of many Wrangel residents, including those who grew up homesteading on the islands that pepper the area. Trips on the river with local guides are highly recommended as they provide, basically, an insider's guide to the Stikine and a very Alaskan way of life. Like much of Southeast, Wrangel has suffered in recent years from a declining resource-based economy. But locals are working to build tourism in the town. Bearfest, which started in 2010, celebrates Wrangel's proximity to Anan Creek, where you can get a close-up view of both brown and black bears. Wrangel has flown three different national flags in its time. Russia established Redoubt St. Dionysius here in 1834. Five years later Great Britain's Hudson's Bay Company leased the southern Alaska coastline, renaming the settlement Ft. Stikine. It was rechristened Wrangel when the Americans took over in 1867; the name came from Baron Ferdinand Petrovich von Wrangel, governor of the Russian-American Company. The rough-around-the-edges town is off the track of the larger cruise ships, so it does not get the same seasonal traffic that Ketchikan and Juneau do. Hence, it is nearly devoid of the souvenir shops that dominate so many other nearby downtown areas. But the gift shops and art galleries that are here do sell locally created work, and the town is very welcoming to visitors; independent travelers would do well to add a stop in Wrangel during their Southeast wanderings.

Rudyerd Bay is one of the highlights of the Misty Fiords, 40 miles east of Ketchikan, along the Inside Passage. This fjord cuts through steep-sided mountainous terrain and extends far into the mainland. The scenery is stunning, with dramatic thousand-foot waterfalls plunging down rainforest covered cliffs to the water below.

Just 40 mi (66 km) south of the Alaskan border, Prince Rupert is the largest community on British Columbia's north coast. Set on Kaien Island at the mouth of the Skeena River and surrounded by deep green fjords and coastal rain forest, Prince Rupert is rich in the culture of the Tsimshian, people who have been in the area for thousands of years. As the western terminus of Canada's second transcontinental railroad and blessed with a deep natural harbor, Prince Rupert was, at the time of its incorporation in 1910, poised to rival Vancouver as a center for trans-Pacific trade. This didn't happen, partly because the main visionary behind the scheme, Grand Trunk Pacific Railroad president Charles Hays, went down with the Titanic on his way back from a financing trip to England. Prince Rupert turned instead to fishing and forestry. A port of call for both BC and Alaska ferries, but relatively new to cruise ships, this community of 15,000 retains a laid-back, small-town air.

Alert Bay is a small village on Cormorant Island, with approximately 1,300 residents. More than half are First Nations people. The settlement was named in 1860 in honour of the Royal Navy ship HMS Alert, which conducted survey operations in the area. The traditional Kwakwaka’wakw people of Alert Bay have endured a difficult history of devastating foreign diseases and failed government policies of assimilation. Today there is a revival of their traditions. One of the most well-known features in Alert Bay is the 173 foot wooden carved totem pole, claimed by some to be the tallest totem pole in the world.

Vancouver is a delicious juxtaposition of urban sophistication and on-your-doorstep wilderness adventure. The mountains and seascape make the city an outdoor playground for hiking, skiing, kayaking, cycling, and sailing—and so much more—while the cuisine and arts scenes are equally diverse, reflecting the makeup of Vancouver's ethnic (predominantly Asian) mosaic. Vancouver is consistently ranked as one of the world's most livable cities, and it's easy for visitors to see why. It's beautiful, it's outdoorsy, and there's a laidback West Coast vibe. On the one hand, there's easy access to a variety of outdoor activities, a fabulous variety of beaches, and amazing parks. At the same time, the city has a multicultural vitality and cosmopolitan flair. The attraction is as much in the range of food choices—the fresh seafood and local produce are some of North America's best—as it is in the museums, shopping, and nightlife.Vancouver's landscaping also adds to the city's walking appeal. In spring, flowerbeds spill over with tulips and daffodils while sea breezes scatter scented cherry blossoms throughout Downtown; in summer office workers take to the beaches, parks, and urban courtyards for picnic lunches and laptop meetings. More than 8 million visitors each year come to Vancouver, Canada's third-largest metropolitan area. Because of its peninsula location, traffic flow is a contentious issue. Thankfully, Vancouver is wonderfully walkable, especially in the downtown core. The North Shore is a scoot across the harbor, and the rapid-transit system to Richmond and the airport means that staying in the more affordable ’burbs doesn't have to be synonymous with sacrificing convenience. The mild climate, exquisite natural scenery, and relaxed outdoor lifestyle keep attracting residents, and the number of visitors is increasing for the same reasons. People often get their first glimpse of Vancouver when catching an Alaskan cruise, and many return at some point to spend more time here.